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Vancomycin
Patient
A priori
Bolus infusion
Continuous infusion
A posteriori
Bolus infusion
Continuous infusion
Advanced modelling
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Demographics
Patient ID (optional)
Sex
Female
Male
Weight (kg)
Age (years)
Select 'yes' if patients undergoes hemodialysis
Hemodialysis
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No
Creatinine
Select if one (single) or more (multiple) measurements are available
Creatinine measurements
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Multiple
Serum creatinine value
mg/dL
µmol/L
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A priori - Bolus infusion
Limits
Target range (mg/L)
Minimal Inhibitory Concentration
MIC (mg/L)
Time (x) up to which the area under the concentration-time curve (AUC₀–x) shall be calculated
AUC duration (h)
Dose recommendation parameters
Dose
250 mg
500 mg
750 mg
1000 mg
1250 mg
1500 mg
2000 mg
Dose interval
6 hours
8 hours
10 hours
12 hours
24 hours
Infusion duration (h)
Compare
Alternative regimen
Dose (mg)
Infusion duration (h)
Dose interval (h)
Calculate
Dose recommendation
Alternative regimen
A priori - Continuous infusion
Limits
Target range (mg/L)
Minimal Inhibitory Concentration
MIC (mg/L)
Time (x) up to which the area under the concentration-time curve (AUC₀–x) shall be calculated
AUC duration (h)
Dose recommendation parameters
Daily dose
500 mg/24 h
750 mg/24 h
1000 mg/24 h
1500 mg/24 h
2000 mg/24 h
2500 mg/24 h
3000 mg/24 h
Loading dose
0 mg
500 mg
750 mg
1000 mg
1500 mg
2000 mg
Duration of loading dose infusion
Infusion duration (h)
Compare
Alternative regimen
Daily dose (mg/24h)
Loading dose (mg)
Duration of loading dose infusion
Infusion duration (h)
Calculate
Dose recommendation
Alternative regimen
A posteriori - Bolus infusion
PK parameters estimation
Exploration
Dosing information
Time of last dose
Dose (mg)
Dose interval (h)
Infusion duration (h)
Measurement
after 1 dose
after 2 doses
after 3 doses
after 4 doses
after 5 doses
in steady state
Level prediction for
total concentration
First measurement
Time of blood sampling
Total concentration
Second measurement (optional)
Time of blood sampling
Total concentration
Estimate PK parameters
Limits
Target range (mg/L)
Minimal Inhibitory Concentration
MIC (mg/L)
Time (x) up to which the area under the concentration-time curve (AUC₀–x) shall be calculated
AUC duration (h)
Dose recommendation parameters
Dose
250 mg
500 mg
750 mg
1000 mg
1250 mg
1500 mg
2000 mg
Dose interval
6 hours
8 hours
10 hours
12 hours
24 hours
Infusion duration (h)
Compare
Alternative regimen
Dose (mg)
Infusion duration (h)
Dose interval (h)
Calculate
Estimated PK parameters
Dose recommendation
Alternative regimen
A posteriori - Continuous infusion
PK parameters estimation
Exploration
Dosing information
Date treatment initiation
Daily dose (mg/24h)
Loading dose
Duration of loading dose infusion
Infusion duration (h)
Level prediction for
total concentration
First measurement
Time of blood sampling
Total concentration
Second measurement (optional)
Time of blood sampling
Total concentration
Estimate PK parameters
Limits
Target range (mg/L)
Minimal Inhibitory Concentration
MIC (mg/L)
Time (x) up to which the area under the concentration-time curve (AUC₀–x) shall be calculated
AUC duration (h)
Dose recommendation parameters
Daily dose
500 mg/24 h
750 mg/24 h
1000 mg/24 h
1500 mg/24 h
2000 mg/24 h
2500 mg/24 h
3000 mg/24 h
Loading dose
0 mg
500 mg
750 mg
1000 mg
1500 mg
2000 mg
Duration of loading dose infusion
Infusion duration (h)
Compare
Alternative regimen
Daily dose (mg/24h)
Loading dose (mg)
Duration of loading dose infusion
Infusion duration (h)
Calculate
Estimated PK parameters
Dose recommendation
Alternative regimen
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Efficacy prediction at
Limits
Target range (mg/L)
Minimal Inhibitory Concentration
MIC (mg/L)
Time (x) up to which the area under the concentration-time curve (AUC₀–x) shall be calculated
AUC duration (h)
Vancomycin administrations
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Vancomycin measurements
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Version 1.2 (24.06.2025)